Weight off Permanently Program

Off-label drugs for weight management

The global pandemic of obesity and overweight now affects between 2.8 and 3.5 billion of the world population and shows no signs of abatement. Treatment for what is now recognized as a chronic disease includes pharmacotherapy, considered an essential component of comprehensive therapy. New drug discovery is robust, but the pace of the US Food and Drug Administration approval for obesity drugs h...

Permanently Implanted Transvenous Pacemakers

Three patients with complete heart block had a high resistance to electrical stimulation of the endocardium through transvenous pacemaker systems. One patient died; one needed reoperation for implantation of epicardial electrodes; and the third required a generator of higher current. The present enthusiasm for permanent transvenous implantation of pacemakers must be tempered somewhat by the kno...

New aerospace medicine program takes off.

Neonatal handling permanently alters hypothalamic-pituitary- adrenal axis function, behaviour, and body weight in boars.

Neonatal handling permanently alters hypothalamic- pituitary-adrenal axis (HPA) function in rats. In the rat, this treatment increases hippocampal glucocorticoid receptors (GR) and dampens plasma ACTH and corticosterone responses to stressors. The objectives of this study were to determine whether neonatal handling of pigs would effect permanent changes in plasma corticosteroid binding capacity...

Permanently Implanted Transvenous

Three patients with complete heart block had a high resistance to electrical stimulation of the endocardium through transvenous pacemaker systems. One patient died; one needed reoperation for implantation of epicardial electrodes; and the third required a generator of higher current. The present enthusiasm for permanent transvenous implantation of pacemakers must be tempered somewhat by the kno...